This paper summarizes the influence of toxicity of Cu2+, Zn2+, Cd2+ and Pb2+ on eggs hatching and survival of nauplius of Penaeus orientalis from the Haiyang Hatchery under different PH and salinity. The 50% egg hatchability concenttrations were 0.165mg/L for Zn2+, 0.072mg/L for Cd2+, 1.88mg/L for Pb2+ and 0.0065mg/L for Cu2+. The LC50 96h (Median Lethal Tolerance Limit) of the four heavy metal ions for nauplius of Penaeus orientalis tested 0.048mg/L for Zn2+, 0.033mg/L for Cd2+, 0.174mg/L for Pb2+ and 0.018mg/L for Cu2+. The results showed the toxic order of these metals to be Cu2+ > Cd2+ > Zn2+ > Pb2+ for the hatching of eggs and the survival of nauplius.